Share this article on:

Plasma catecholamine and blood lactate responses to incremental arm and leg exercise

SCHNEIDER, DONALD A.; McLELLAN, TOM M.; GASS, GREG C.

Medicine & Science in Sports & Exercise: March 2000 - Volume 32 - Issue 3 - p 608-613
BASIC SCIENCES: Original Investigations

SCHNEIDER, D. A., T. M. McLELLAN, and G. C. GASS. Plasma catecholamine and blood lactate responses to incremental arm and leg exercise. Med. Sci. Sports Exerc., Vol. 32, No. 3, pp. 608–613, 2000. Purpose and

Methods: The present study was conducted to examine the pattern of plasma catecholamine and blood lactate responses to incremental arm and leg exercise. Seven untrained male subjects performed two incremental exercise tests on separate days in random order. One test consisted of 1-arm cranking (5W·2 min−1), whereas the other exercise test was 2-leg cycling (20–25W·2 min−1). Blood samples were obtained from the nonexercising arm during 1-arm cranking and from the same arm and vein during 2-leg cycling. Thresholds for blood lactate (TLa), epinephrine (TEpi) and norepinephrine (TNE) were determined for each subject under both exercise conditions and defined as breakpoints when plotted as a function of power output.

Results: When the two modes of exercise were compared, TLa, TEpi, and TNE were all significantly lower for 1-arm cranking than for 2-leg cycling (P < 0.01). During 1-arm cranking, TLa (0.96 ± 0.10 L·min−1), TEpi (1.02 ± 0.07 L·min−1), and TNE (1.07 ± 0.09 L·min−1) occurred simultaneously. During 2-leg cycling, TLa (1.77 ± 0.20 L·min−1), TEpi (1.74 ± 0.17 L·min−1), and TNE (1.98 ± 0.17 L·min−1) occurred at similar levels of O2 and were not significantly different. The correlation observed between the O2 measured at the TLa and TEpi was 0.917 for arm and 0.929 for leg exercise (P < 0.001). The epinephrine concentration ([Epi]) obtained at the TLa was not significantly different for arm (0.144 ng·mL−1) and leg (0.152 ng·mL−1) exercise.

Conclusions: The breakpoint in plasma [Epi] shifted in an identical manner and occurred simultaneously with that of TLa regardless of the mode of exercise (arm or leg). The Epi concentrations observed at the TLa agree with those previously reported to produce a rise in blood lactate during Epi infusion at rest. These results support the hypothesis that a rise in plasma [Epi] may contribute to the breakpoint in blood lactate that occurs during incremental exercise.

Exercise Science Research Laboratory, School of Physiotherapy and Exercise Science, Griffith University, Gold Coast, Queensland 9726, AUSTRALIA; and Human Protection and Performance Section, Defence and Civil Institute of Environmental Medicine, North York, Ontario M3M3B9, CANADA

Submitted for publication July 1998.

Accepted for publication March 1999.

Address for correspondence: Donald A. Schneider Ph.D., School of Physiotherapy and Exercise Science, Griffith University - Gold Coast, PMB 50 Gold Coast Mail Centre, Southport, Queensland 9726, Australia. E-mail: D.Schneider@mailbox.gu.edu.au.

©2000The American College of Sports Medicine