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Cardiovascular and hormonal changes induced by isolation and confinement

MAILLET, A.; GAUQUELIN, G.; GHARIB, C.

Medicine & Science in Sports & Exercise: October 1996 - Volume 28 - Issue 10 - p 53-55
International Workshop on Cardiovascular Rearch in Space: Body Fluid Metabolism and Control of Intravascular Volume

The cardiovascular changes induced by microgravity are in general described as the result of the loss of hydrostatic pressure. Other factors are also important: restricted environment with 1) elimination of mobility, action and 2) isolation always found in space environment or during simulation studies. Several studies indicate an analogy between microgravity and confinement. The results of simulation studies could be misinterpreted without a control confinement study present in the protocol.

Labortatoire de Physiologie de l'Environnement, (GIP-Exercise, DRET and CNES) Faculté de Médecine Grange Blanche, F-69373 Lyon Cedex 08, FRANCE

Submitted for publication December 1995.

Accepted for publication May 1996.

Address for correspondence: C. Gharib, Labortatoire de Physiologie de l'Environnement, (GIP-Exercise-DRET), Faculté de Médecine Grange Blanche, 8, avenue Rockefeller, F-69373 Lyon Cedex 08, France.

©1996The American College of Sports Medicine