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Frank W. Booth, PhD, FACSM
Video Abstract for the ESSR 45.4 article “Mechanisms Associated With Physical Activity
Behavior: Insights From Rodent Experiments” from authors Michael D. Roberts, Gregory N. Ruegsegger, Jacob D. Brown, and Frank W. Booth. Dopaminergic signaling differences in the nucleus accumbens (NAcc) seemingly predispose rats to adopt different physical activity behaviors. Physical activity behavior also may be regulated through peripheral mechanisms (i.e., muscle and fat derived as well as hormonal signals). We hypothesize that physical activity behavior is regulated by the convergence of central and peripheral mechanisms onto the NAcc.