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Arterial Baroreflex Resetting During Exercise in Humans

Underlying Signaling Mechanisms

Raven, Peter B.1; Young, Benjamin E.2; Fadel, Paul J.2

Exercise and Sport Sciences Reviews: July 2019 - Volume 47 - Issue 3 - p 129–141
doi: 10.1249/JES.0000000000000190
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The arterial baroreflex (ABR) resets during exercise in an intensity-dependent manner to operate around a higher blood pressure with maintained sensitivity. This review provides a historical perspective of ABR resetting and the involvement of other neural reflexes in mediating exercise resetting. Furthermore, we discuss potential underlying signaling mechanisms that may contribute to exercise ABR resetting in physiological and pathophysiological conditions.

This review provides a historical perspective of arterial baroreflex resetting during exercise, and the potential underlying signaling pathways involved.

1Department of Integrative Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth; and

2Department of Kinesiology, University of Texas at Arlington, Arlington, TX

Address for correspondence: Peter B. Raven, Ph.D., Department of Integrative Physiology and Anatomy, University of North Texas Health Science Center, 3500 Camp Bowie Blvd, Fort Worth, TX 76107, USA (E-mail: peter.raven@unthsc.edu).

Accepted for publication: March 18, 2019.

Editor: Philip S. Clifford, Ph.D., FACSM.

Online date: March 28, 2019

© 2019 American College of Sports Medicine