Institutional members access full text with Ovid®

Share this article on:

Protective Effects of Exercise on Cognition and Brain Health in Older Adults

Tyndall, Amanda V.1,2; Clark, Cameron M.1,2; Anderson, Todd J.3,4; Hogan, David B.2,5,6,7; Hill, Michael D.2,5,6; Stewart Longman, R.2,8,9; Poulin, Marc J.1,2,4,5,10,11

doi: 10.1249/JES.0000000000000161
Brief Review: PDF Only

Accelerated trajectories of cognitive decline in older adults may increase the risk of developing Alzheimer disease and related dementias (ADRD). Physical activity has potential modifying effects on these changes that could prevent and/or delay ADRD. This review explores the hypothesis that multiple, mutually complimentary and interacting factors explain the positive association between exercise and the optimization of cognition in older adults.

1 Department of Physiology & Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

2 Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

3 Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

4 Libin Cardiovascular Institute of Alberta, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

5 Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

6 Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

7 Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

8 Department of Psychology, University of Calgary, Calgary, Alberta, Canada

9 Psychology Service, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada

10 Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada

11O’Brien Institute for Public Health, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

Correspondence: Marc J. Poulin, PhD, DPhil, Professor, Department of Physiology & Pharmacology, Brenda Strafford Foundation Chair in Alzheimer Research, Cumming School of Medicine, University of Calgary, HMRB-210, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, CANADA, Phone: 1.403.220.8372; Fax: 1.403.210.8420

No Disclosures to Report

© 2018 American College of Sports Medicine