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The Microvasculature and Skeletal Muscle Health in Aging

Landers-Ramos, Rian Q.1,2; Prior, Steven J.1,2,3

Exercise and Sport Sciences Reviews: July 2018 - Volume 46 - Issue 3 - p 172–179
doi: 10.1249/JES.0000000000000151
Video Abstract

Aging and aging-related declines in physical activity are associated with physical and metabolic impairments. Skeletal muscle capillarization is reduced in sedentary older adults, may contribute to impairments in skeletal muscle, and is modifiable by exercise training. This article examines the hypothesis that preservation of skeletal muscle capillarization is essential to maintain metabolism, fitness, and function with aging.

The maintenance of capillarization is a critical component of skeletal muscle mass, fitness, and metabolism in aging.

1Baltimore Veterans Affairs Geriatric Research, Education and Clinical Center;

2Department of Medicine, University of Maryland School of Medicine, Baltimore; and

3Department of Kinesiology, University of Maryland School of Public Health, College Park, MD

Address for correspondence: Steven J. Prior, Ph.D., Department of Kinesiology, University of Maryland School of Public Health, 4200 Valley Dr, Room 2134D, College Park, MD 20742 (E-mail:

Accepted for publication: March 14, 2018.

Editor: Marni D. Boppart, Sc.D., FACSM.

© 2018 American College of Sports Medicine