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Arterial Ventricular Uncoupling With Age and Disease and Recoupling With Exercise

Chantler, Paul D.

Exercise and Sport Sciences Reviews: April 2017 - Volume 45 - Issue 2 - p 70–79
doi: 10.1249/JES.0000000000000100

The deterioration in arterial and cardiac function with aging impairs arterial ventricular coupling, an important determinant of cardiovascular performance. However, exercise training improves arterial ventricular coupling especially during exercise. This review examines the concept of arterial-ventricular coupling and how age and disease uncouples, but exercise training recouples, the heart and arterial system.

Can exercise training recouple the interaction between the heart and arterial system.

1Division of Exercise Physiology, School of Medicine; and 2Center for Cardiovascular and Respiratory Sciences, Health Sciences Center, West Virginia University, Morgantown, WV

Address for correspondence: Paul D. Chantler, Ph.D., Robert C. Byrd Health Sciences Center, Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV 26506 (E-mail:

Accepted for publication: October 17, 2016

Editor: Hirofumi Tanaka, Ph.D., FACSM

© 2017 American College of Sports Medicine