​​​​​​​​​​​​​​​​​​​​Practice Guidelines

AASLD develops evidence-based practice guidelines, practice guidances, and patient guidances  to share recommended approaches to the diagnostic, therapeutic, and preventive aspects of care. View the AASLD Policy here.

AASLD guidelines use clinically relevant questions, which are then answered by systematic reviews of the literature, and followed by data-supported recommendations. The guidelines are developed by a multidisciplinary panel of experts who rate the quality (level) of the evidence and the strength of each recommendation using the Grading of Recommendations Assessment, Development, and Evaluation system. 

AASLD guidance statem​​​​ents are put forward to help clinicians understand and implement the most recent evidence based on comprehensive review and analysis of the literature. Recently AASLD has published guidances on aspects of a topic that lacked sufficient data to perform systematic reviews.  

AASLD also develops quality measures to help its members measure or quantify healthcare processes and outcomes that are associated with the ability to provide high-quality health care. AASLD’s Cirrhosis Quality Collaborative​ network​ combines quality improvement and research to improve the care and treatment outcomes of patients with cirrhosis.

Read more about practice guideline development and about AASLD’s conflict of interest policy in articles excerpted from the Hepatology Journal, or review AASLD's Code for the Assessment and Management of Conflict of Interest.​

​​​Guidelines and Guidance by Disease​

Acute Liver Failure, Management

Alcohol-Associated Liver Disease

Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome, Management​

Autoimmune Hepatitis, Management

Drug, Herbal, and Dietary Supplement-induced Liver Injury 

Hemochromatosis, Management

Hepatic Encephalopathy

Hepatitis B, Chronic

Hepatitis C, Guidance

Hepatocellular Carcinoma, Management

Liver Biopsy​​​

Liver Transplantation, Evaluation of the Adult Patient

Liver Transplantation, Evaluation of the Pediatric Patient

Long-Term Management of the Adult Liver Transplant

​Long-Term Management of the Pediatric Liver Transplant

Malnutrition, Frailty, and Sarcopenia in Patients with Cirrhosis

Non-Alcoholic Fatty Liver Disease, Diagnosis and Management

Palliative Care and Symptom-Based Management for Decompensated Cirrhosis

Portal Hypertension Bleeding in Cirrhosis, Guidance

Portal Hypertension, Management and Tips

Primary Biliary Cholangitis

Primary Sclerosing Cholangitis and Cholangiocarcinoma

Reproductive Health and Liver Disease

Vascular Disorders of the Liver

Wilson Disease, Diagnosis and Treatment

​​Guidelines and Guidances in Development 



​​Quality Measures

Quality measures are a tool for providers and institutions to evaluate their care quality, drive quality improvement, and deliver high-value patient care

View Quality Measures

​Patient Guidelines

Patient Guidances are adaptations of published AASLD guidances which are written specifically for patients to help them understand their liver disease. Clinicians may also provide these patient guidances to their patients as a resource during consultations.​​

View Patient Guidelines

​​Citing Practice Guidelines and Guidances

​​AASLD practice guidelines and guidances are copyright protected. One copy may be accessed for personal research, scientific, scholarly or informational purposes and may be transmitted to a third-party colleague in hard copy or electronically for similar use. One figure, table or brief excerpt less than 400 words may be used in one’s scientific, scholarly and educational work with appropriate credit. 

Permission is required to reproduce more than one figure, table, or section over 400 words or complete practice guidelines and guidances for systematic redistribution. Re-sale and posting AASLD practice guidelines and guidances on other websites are not allowed; however, linking to these documents is permitted. Contact [email protected] for assistance. 

​Related Information

Fundamentals of Liver Diseases

This robust program offers learners everything they need to know about the basics of liver disease. If you’re new to the field, encounter liver disease in your patients, or just looking to brush up on your Hepatology 101, this free course is for you.

Conflict of Interest

​​AASLD must insure that its membership, leadership and the public-at-large understand the importance it places on identification and resolution of conflicts.​


Liver Connect Forums

Liver Connect Forums is an exclusive member forum where you can connect with experts on a variety of topics to help advance the science of hepatology. ​

Join the Conv​​ersation

COVID-19 and the Liver

AASLD created a variety of resources to help hepatologists and liver patients navigate COVID-19.​

Stay Informed