Kounis Syndrome During Anesthesia: Presentation of Indolent Systemic Mastocytosis: A Case Report : A&A Practice

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Kounis Syndrome During Anesthesia: Presentation of Indolent Systemic Mastocytosis: A Case Report

de la Fuente Tornero, Elena MD*; Vega Castro, Arantza MD; de Sierra Hernández, Pedro Álvarez PhD; Balaguer Recena, Javier MD§; Zaragoza Casares, Sofía Carmen MD*; Serrano Baylin, Francisco Miguel MD*; Gallardo Culebradas, Paloma MD*; Amorós Alfonso, Beatriz MD*; Rodríguez Fraile, Jose Ramón MD*

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A & A Case Reports 8(9):p 226-228, May 1, 2017. | DOI: 10.1213/XAA.0000000000000474

Abstract

Mastocytosis comprises a heterogeneous group of disorders characterized by mast cell accumulation and proliferation in distinct organs. Kounis syndrome is defined as the concurrence of acute coronary syndromes with mast cell activation in a setting of allergic or hypersensitivity reactions. This is the first reported case of an intraoperative Kounis syndrome as the onset of an indolent systemic mastocytosis probably triggered by succinylated gelatin infusion during general anesthesia. The presentation of this case is intended to contribute to the knowledge of mastocytosis and Kounis syndrome at the time of diagnostic workup during intraoperative anaphylaxis or myocardial ischemia.

Copyright © 2017 International Anesthesia Research Society

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