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Acute Adrenal Insufficiency After an Antiemetic Dose of Dexamethasone: A Case Report

Bacigalupo Landa, Andres MD*; Viswanath, Omar MD†,‡; D’Mello, Jayanand MD, FRCA§

doi: 10.1213/XAA.0000000000000953
Case Reports

Dexamethasone is widely used in current practice for the prevention of postoperative nausea and vomiting. Although its use in the perioperative setting has been associated with several side effects (eg, hyperglycemia and suppression of adrenal cortisol production), their clinical significance remains questionable. We present the case of a healthy 27-year-old woman who developed acute adrenal insufficiency after receiving intraoperative dexamethasone for postoperative nausea and vomiting prophylaxis during a laparoscopic left oophorectomy.

From the *Department of Anesthesiology, Mount Sinai Medical Center, Miami Beach, Florida

University of Arizona College of Medicine-Phoenix, Phoenix, Arizona

Creighton University School of Medicine, Omaha, Nebraska

§Miami Beach Anesthesiology Associates, Inc, Department of Anesthesiology, Mount Sinai Medical Center, Miami Beach, Florida.

Accepted for publication November 20, 2018.

Funding: None.

The authors declare no conflicts of interest.

Address correspondence to Andres Bacigalupo Landa, MD, Department of Anesthesiology, Mt Sinai Medical Center, 4300 Alton Rd, Miami Beach, FL 33140. Address e-mail to

Copyright © 2019 International Anesthesia Research Society
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