A 26-year-old male patient with hypofibrinogenemia was scheduled to undergo tonsillectomy. Hypofibrinogenemia, defined as low plasma fibrinogen (Fbg) concentration, is a type of congenital Fbg deficiency and is a rare coagulopathy. Perioperative replenishment of Fbg is performed during minor surgeries, aimed at maintaining plasma Fbg concentrations of 50 mg/dL. In this case, failure to replenish Fbg during the postoperative period may have caused the postoperative hemorrhage. Considering the half-life of Fbg (3–4 days), the plasma Fbg concentration should be monitored for ≥6 postoperative days, aiming at a target level of 50 mg/dL during the postoperative period.
From the Department of Anesthesiology, Kawasaki Municipal Hospital, Kawasaki City, Kanagawa, Japan.
Accepted for publication August 24, 2018.
The authors declare no conflicts of interest.
Address correspondence to Yoshimune Osaka, MD, PhD, Department of Anesthesiology, Kawasaki Municipal Hospital, 12-1 Shinkawa St, Kawasaki-ku, Kawasaki City, Kanagawa 210-0013, Japan. Address e-mail to email@example.com.