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Bovine Hemoglobin-Based Oxygen Carrier Treatment in a Severely Anemic Jehovah’s Witness Patient After Cystoprostatectomy and Nephrectomy

A Case Report

Brotman, Ian, MD; Kocher, Matthew, BS; McHugh, Stephen, MD

doi: 10.1213/XAA.0000000000000901
Case Reports

Patients who are Jehovah’s Witnesses are known to the medical community for frequently declining blood products, even at times of life-threatening anemia. Alternatives to red blood cell transfusion are being developed, including hemoglobin (Hb)-based oxygen carriers. We present the case of a 77-year-old male Jehovah’s Witness who underwent a cystoprostatectomy and radical nephrectomy with a postoperative Hb nadir of 4.5 g/dL. He received an Hb-based oxygen carrier, PEGylated carboxyhemoglobin bovine (Sanguinate), with gradual improvement in anemia symptoms and eventual discharge to a short-term rehabilitation facility.

From the Department of Anesthesiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Accepted for publication August 21, 2018

Funding: None.

The authors declare no conflicts of interest.

Address correspondence to Stephen McHugh, MD, University of Pittsburgh Department of Anesthesiology, 5230 Centre Ave, Pittsburgh, PA 15232. Address e-mail to

© 2019 International Anesthesia Research Society
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