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Management of a Patient With a History of Nonanesthesia-Related Malignant Hyperthermia Undergoing Laparoscopic Cholecystectomy: A Case Report

Nelson, Emily P., MD*; Dorlon, Margaret E., MD; Szabo, Tamas A., MD, PhD*; Trollinger, Jonathan B., CRNA; Johnson-Mann, Crystal, MD; Broderick, Gearin, MD*; Warters, Robert D., MD*

doi: 10.1213/XAA.0000000000000767
Case Reports

A 36-year-old African American with a medical history of nonanesthesia-related malignant hyperthermia (MH) who was taking chronic oral dantrolene therapy presented with right upper quadrant pain for a laparoscopic cholecystectomy. A multidisciplinary perioperative plan was implemented with the goal of avoiding triggering an MH episode or rhabdomyolysis. He developed a postoperative left brachial vein thrombus of unclear etiology, possibly related to dantrolene administration or his underlying susceptibility to MH.

From the Departments of *Anesthesia and Perioperative Medicine

Surgery, Medical University of South Carolina, Charleston, South Carolina

Department of Anesthesiology, Ralph H. Johnson VA Medical Center, Charleston, South Carolina.

Accepted for publication February 16, 2018.

Funding: None.

The authors declare no conflicts of interest.

Emily P. Nelson, MD, and Margaret E. Dorlon, MD, contributed equally to this work.

Address correspondence to Tamas A. Szabo, MD, PhD, Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, 167 Ashley Ave, Suite 301, MSC912, Charleston, SC 29425. Address e-mail to

© 2018 International Anesthesia Research Society
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