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The Use of Sugammadex in a Patient With Guillain–Barre Syndrome: A Case Report

Tezcan, Büşra MD; Bölükbaşi, Demet MD; Kazanci, Dilek MD; Turan, Sema MD; Suer Kaya, Gülseren MD; Özgök, Ayşegül MD

doi: 10.1213/XAA.0000000000000465
Case Reports: Case Report

Sugammadex encapsulates and inactivates rocuronium and vecuronium. It is used to reverse neuromuscular blockade from these nondepolarizing agents. The safety of sugammadex in patients with neuromuscular disease has not been established. Guillain–Barre Syndrome (GBS) is a neuromuscular disease characterized by acute inflammatory polyneuropathy. Patients with GBS may exhibit autonomic dysfunction, chronic pain, abnormal reactions to neuromuscular blocking agents, and may require postoperative mechanical ventilation. We report the successful use of sugammadex to reverse rocuronium in a patient with chronic GBS, who presented for a hemicolectomy.

From the Department of Anesthesiology and Reanimation Clinic, Turkey Yüksek Ihtisas Education and Research Hospital, Ankara, Turkey.

Accepted for publication October 21, 2016.

Funding: None.

The authors declare no conflicts of interest.

Address correspondence to Büşra Tezcan, MD, Department of Anesthesiology and Reanimation, Turkey Yüksek Ihtisas Education and Research Hospital, Türkiye Yüksek İhtisas Hastanesi B polk No 10 Sihhiye, Ankara, Turkey. Address e-mail to

© 2017 International Anesthesia Research Society
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