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Benign Liver Masses: Imaging With Microbubble Contrast Agents

Kim, Tae Kyoung MD*; Jang, Hyun-Jung MD†; Wilson, Stephanie R. MD‡

Ultrasound Quarterly:
Original Articles: CME Article
Abstract

Abstract: Benign focal liver lesions are frequently encountered in routine ultrasound (US) scanning as well as in staging US examination for the patients with known malignancy. Noninvasive characterization of benign liver masses by imaging features has been a challenge for the radiologist. Some benign liver masses show typical findings on US; however, these findings are not highly specific. Contrast-enhanced ultrasound (CEUS) is useful to make an instant, confident diagnosis of benign liver masses. Contrast-enhanced multiphasic computed tomography (CT) is an excellent imaging technique to detect and characterize focal liver masses. But there are a considerable number of indeterminate focal liver lesions, which require further evaluation. CEUS provides the evaluation of perfusion and hemodynamics of nodular liver lesions as well as real-time morphologic evaluation of lesion vascularity. Most benign liver masses show characteristic features on CEUS, allowing an accurate diagnosis. This review article describes typical enhancement features of common benign liver masses.

Author Information

*Radiologist, Associate Professor, Toronto General Hospital, University of Toronto, Ontario, Canada; † Radiologist, Assistant Professor, Toronto General Hospital, University of Toronto, Ontario, Canada; and ‡Radiologist, Professor, Toronto General Hospital, University of Toronto, Ontario, Canada.

Dr. Kim has disclosed that he received direct research funds from Bristol-Myers Squibb for Phase III trial of Definity.

Dr. Jang has disclosed that he has received grant/research funds from Bristol-Myers Squibb.

Dr. Wilson has disclosed that she received grant/research funds from Bristol-Myers Squibb and is a consultant/advisor for Philips, Siemens.

Wolters Kluwer Health has identified and resolved all faculty conflicts of interest regarding this educational activity.

Reprints: Tae Kyoung Kim, Department of Medical Imaging, Toronto General Hospital, University of Toronto, 585 University Avenue, Toronto, Ontario, Canada M5G 2N2 (e-mail: mailto: taekyoung.kim@uhn.on.ca).

© 2006 Lippincott Williams & Wilkins, Inc.