Retroperitoneoscopic Donor Nephrectomy With Multiple Renal Arteries Does Not Affect Graft Survival and Ureteral Complications

Omoto, Kazuya1,2; Nozaki, Taiji1; Inui, Masashi1; Hirai, Toshihito1; Sawada, Yugo1; Shimizu, Tomokazu1; Toki, Daisuke1; Ishida, Hideki1; Tanabe, Kazunari1

Transplantation:
doi: 10.1097/TP.0000000000000326
Clinical and Translational Research
Abstract

Background: Outcomes of retroperitoneoscopic procurement of living kidneys with multiple renal arteries (MRA) in the recipients are largely unknown. Our aim is to access the effect of kidney allografts with MRA on donor and recipient outcomes after pure retroperitoneoscopic live donor nephrectomy (RPLDN).

Methods: From July 2001 to August 2010, 533 patients underwent live donor kidney transplants with allografts procured by RPLDN at our center. Of these 533 transplants, 406, 105, and 22 patients had one, two, and three renal arteries, respectively. We compared the retrospectively collected clinical data of each donor with MRA and the recipient using those with single renal artery as controls.

Results: Significant differences were found among the one–renal artery and three–renal artery groups regarding operative time, estimated blood loss, warm and cold ischemic time, and incidence of slow graft function (SGF). However, there was no significant difference regarding patient and graft survival among the three groups. Major complications, such as open conversion, bleeding, and blood transfusion, were not found in patients with MRA. Five ureteral complications occurred. Of these, there was one patient with MRA. In univariate analysis, MRA patients had a risk factor of developing SGF (P=0.005) but not ureteral complications following RPLDN.

Conclusion: Kidneys with MRA after RPLDN increase the risk of SGF in recipients. However, they provide similar outcomes as to long-term graft survival and complications compared with those of single renal artery. Renal artery multiplicity should not be a contraindication for live kidney donation and may not increase the risk of ureteral complications.

Author Information

1 Department of Urology, Tokyo Women’s Medical University.

2 Address correspondence to: Kazuya Omoto, M.D., Ph.D., Department of Urology, Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

The authors declare no funding or conflicts of interest.

E-mail: omotokazuya@yahoo.co.jp

K.O. and K.T. participated in the research design, writing of the manuscript, performance of the research, and data analysis. T.N., M.I., T.H., Y.S., T.S., D.T., and H.I. carried out the research.

Received 9 December 2013. Revision requested 26 December 2013.

Accepted 27 May 2014.

Accepted July 23, 2014

© 2014 by Lippincott Williams & Wilkins