Osteonecrosis of the jaw & osteoporosis therapy

Kessenich, Cathy R.

Nurse Practitioner . 35(7):51-53, July 2010.

According to a task force convened by the American Society of Bone and Mineral Research, the risk of osteonecrosis of the jaw (ONJ) associated with oral bisphosphonate therapy for osteoporosis is low and estimated at 1 in 10,000 and less than 1 in 100,000 patient-treatment years. Comparatively, the risk of ONJ in patients with cancer treated with high doses of intravenous bisphosphonates is higher and estimated at 1-10 per 100 patients treated.

Osteoporosis: New Options for Pain Relief

Kessenich, Cathy R.

Nurse Practitioner . 31(2):44-47, February 2006.

Advances in diagnostic testing and pharmacologic treatments have helped identify risks of osteoporotic fractures and, subsequently, decreased the incidence and severity of fractures. Two new procedures—vertebroplasty and kyphoplasty—can be useful alternatives for patients who are severely limited by the pain of vertebral fractures and remain nonresponsive to conservative pain relief measures.