INSTRUCTIONS Pharmacologic therapy for female sexual dysfunction
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Pharmacologic therapy for female sexual dysfunction
General Purpose: To provide information on the research and recommendations for practice for treatment of FSD. Learning Objectives: After reading this article and taking the test, the learner should be able to: 1. Identify the classifications and prevalence of FSD. 2. Recognize the clinical evaluation process and the role of nonpharmacologic treatments. 3. Select pharmacologic therapies targeted for categories of FSD.
- A linear model of the female sexual response cycle that is focused on the emotional and psychological factors of FSD, can be found in the
- HRQol questionnaire.
- Decreased Sexual Desire Screener.
- PLISSIT model.
- Which statement concerning FSD is correct?
- FSD is not reported by premenopausal American women.
- FOD is the most prevalent category of FSD.
- Comorbid health conditions may affect the presentation of FSD.
- Researchers use standard methodology to document prevalence of FSD.
- The authors' literature search was narrowed to exclude
- perimenopausal women.
- women in long-term-care facilities.
- women experiencing significant personal distress.
- women under treatment for depression.
- Which physiologic factors primarily affect sexual function in peri- and postmenopausal women?
- serotonin and nitric oxide
- DHEA and serotonin
- norepinephrine and dopamine
- circulating androgens
- FSD secondary to diabetes falls under which FSD category?
- Which FSD screening instrument was developed specifically for use in primary care?
- Changes in Sexual Function Questionnaire
- Decreased Sexual Arousal Screener
- Brief Sexual Symptom Checklist
- Diagnostic lab tests for FSD
- should be based on findings from the history and physical exam.
- routinely include fasting blood glucose and lipid levels.
- focus on hormone levels in premenopausal women.
- determine whether counseling is indicated.
- Which lifestyle intervention demonstrated a significant increase in sexual satisfaction among postmenopausal women with type 2 diabetes?
- smoking cessation
- eating Mediterranean-style diet
- minimizing alcohol intake
- keeping physically active
- Physiotherapy is a suggested nonpharmacologic treatment particularly for
- sexual pain disorders.
- A patient who is post total hysterectomy with HSDD is receiving oral estrogen Which treatment in clinical trials has been found effective in increasing desire?
- transdermal testosterone patch at 150 mcg/day
- silicone estrogen ring
- transdermal testosterone patch at 300 mcg/day
- transdermal estradiol
- The FDA has not approved topical testosterone treatment for women because of its
- strong link to endometrial cancer.
- lack of long-term safety data.
- significant adverse effect on lipid metabolism.
- inconsistent effectiveness data.
- Sexual dysfunction associated with SSRI use may be significantly improved by
- replacing the SSRI with bupropion twice daily.
- using bupropion or placebo.
- increasing the SSRI dosage.
- adding adjunctive bupropion twice daily.
- Investigators found that bremelanotide did not increase BP versus placebo when administered at home as needed by which route?
- Use of PDE-5 inhibitors in women
- are a standard treatment option for FSAD.
- do significantly affect genital engorgement.
- are FDA approved for the treatment of FSD.
- show promise in treating neurodegenerative disorders.
- Which statement is correct concerning estrogen therapy for sexual pain disorders?
- Transdermal estrogen preparations are more effective than local.
- Topical estrogen provides better relief of VVA than systemic therapies.
- Systemic estrogen therapy should be a first-line treatment for VVA.
- Dyspareunia is not relieved by local estrogen therapy.
- Which recently FDA-approved drug is shown to be effective for postmenopausal women with VVA?
- as a topical vaginal preparation, did not improve severity scores for dyspareunia in postmenopausal women.
- can be converted into biologically active steroids.
- has been granted tentative FDA approval.
- should be advised only for those with full adrenal function.