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Nurse Practitioner:
doi: 10.1097/01.NPR.0000398475.15034.3b
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Over-the-counter medications and pregnancy: An integrative review

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INSTRUCTIONS Over-the-counter medications and pregnancy: An integrative review

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Over-the-counter medications and pregnancy: An integrative review

General Purpose: To provide the NP with a review of OTC medications and their use during pregnancy. Learning Objectives: After reading the preceding article and taking the following test, you should be able to: 1. Describe the use of OTC medication during pregnancy. 2. Identify the FDA Risk Classifications in Pregnancy of specific medications. 3. Discuss the advantages and disadvantages of specific OTC medications in pregnancy.

1. The percentage of pregnant women who self-medicate with at least five OTC medications is more than

a. 20%.

b. 40%.

c. 60%.

d. 80%.

2. Which FDA Risk Classification indicates that the drug should be taken in pregnancy only if the potential benefit justifies the potential risk to the fetus?

a. Category A

b. Category B

c. Category C

d. Category D

3. Which pain medication is used by at least 65.5% of women at some point during their pregnancy?

a. acetaminophen

b. ibuprofen

c. aspirin

d. codeine

4. According to Glover et al., as pregnancy progresses, the use of

a. acetaminophen decreases.

b. acetaminophen increases.

c. NSAIDs decreases.

d. NSAIDs increases.

5. Ibuprofen during pregnancy is classified as FDA category

a. A.

b. B.

c. C.

d. D.

6. Ibuprofen taken in the first trimester -increases risk of

a. renal anomalies.

b. miscarriage.

c. neural tube defects.

d. congenital heart defects.

7. Aspirin full dose, when taken in the third trimester, is listed as FDA category

a. A.

b. B.

c. C.

d. D

8. Which medication appears to be the best choice for both pain and fever reduction in pregnant women?

a. acetaminophen

b. ibuprofen

c. full-dose aspirin

d. low-dose aspirin

9. Which cold and allergy medication is -classified during pregnancy as FDA category B?

a. dextromethorphan

b. diphenhydramine

c. guaifenesin

d. pseudoephedrine

10. Which of the following statements about pseudoephedrine is correct?

a. Pseudoephedrine may increase maternal BP and decrease uterine blood flow

b. Approximately 80% of pregnant women take pseudoephedrine during pregnancy.

c. Pseudoephedrine is a potent vasodilator.

d. Pseudoephedrine has no effect on uterine blood flow.

11. The percentage of pregnant women who take some sort of cough medication is more than

a. 12%.

b. 22%.

c. 32%.

d. 42%.

12. Both dextromethorphan and guaifenesin are classified as FDA pregnancy category

a. A.

b. B.

c. C.

d. D.

13. About what percentage of pregnant women have common gastrointestinal complaints such as flatulence, heartburn, and constipation?

a. 45%

b. 65%

c. 75%

d. 90%

14. Which statement about simethicone is correct?

a. It is classified as FDA pregnancy category B.

b. The drug is not absorbed systemically, and considered safe for use in pregnancy.

c. Simethicone use during pregnancy is associated with cardiac defects.

d. It is the only antiflatulent that is systemically absorbed.

15. Kaolin may predispose pregnant women to

a. miscarriage.

b. preeclampsia.

c. gestational diabetes.

d. iron deficiency anemia.

16. Docusate sodium is associated with which congenital defect?

a. gastroschisis

b. congenital heart defect

c. neural tube defect

d. none

17. The first-line antacid drug choice during pregnancy should be

a. calcium-based.

b. magnesium-based.

c. bicarbonate-based.

d. aluminum-based.

18. H2 receptor antagonists during pregnancy are classified as FDA category

a. A.

b. B.

c. C.

d. D.

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