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Journal of Thoracic Imaging:
doi: 10.1097/RTI.0b013e31822031f0
Web Exclusive Content-Pictorial Essays

Therapy-related Noninfectious Complications in Patients With Hematologic Malignancies: High-resolution Computed Tomography Findings

Brodoefel, Harald MD*; Faul, Christoph MD; Salih, Helmut MD; Vogel, Wolfgang MD; Fenchel, Michael MD*,‡; Horger, Marius MD*

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Abstract

Pulmonary complications are a leading source of mortality in patients treated for hematologic malignancies. After hematopoietic stem cell transplantation, treatment-related noninfectious complications constitute more than half of the pulmonary pathology and represent a particular diagnostic challenge. This review illustrates the high-resolution computed tomography findings of common therapy-related complications and thereby demonstrates a high degree of overlap between the patterns of various toxicities. Clinical background knowledge of the distinct entities is reviewed and highlighted as an indispensable instrument to narrow the differential diagnosis.

© 2013 Lippincott Williams & Wilkins, Inc.

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