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Interstitial Pneumonia Associated With Ulcerative Colitis: High-resolution Computed Tomography and Pathologic Findings

Ikehara, Naoko MD*; Fujimoto, Kiminori MD, PhD*,†; Sadohara, Junko MD, PhD*; Iwamoto, Ryoji MD*; Tajiri, Morihiro MD; Okamoto, Masaki MD, PhD; Fukuoka, Junya MD, PhD§

Journal of Thoracic Imaging:
doi: 10.1097/RTI.0b013e3182633a87
Web Exclusive Content-Japanese Society of Thoracic Radiology Meeting Notes
Abstract

Pulmonary parenchymal manifestations associated with ulcerative colitis (UC) include various conditions such as opportunistic infections, interstitial pneumonia, organizing pneumonia, and adverse drug reactions. We present a case of interstitial pneumonia associated with UC in a 61-year-old nonsmoking woman. High-resolution computed tomography demonstrated multifocal ill-defined areas of consolidation and ground-glass attenuation with or without traction bronchiectasis, predominantly in peripheral lung parenchyma. Lung biopsy showed that the closest pathologic pattern in the areas of abnormality was cellular and fibrotic nonspecific interstitial pneumonia. We also discuss the evaluation and treatment of pulmonary disease possibly related to UC in the clinical course of this patient.

Author Information

*Department of Radiology

Department of Medicine, Division of Respirology, Neurology, and Rheumatology, Kurume University School of Medicine

Center for Diagnostic Imaging, Kurume University Hospital, Kurume

§Department of Surgical Pathology, Toyama University Hospital, Toyama, Japan

The authors declare no conflicts of interest.

Reprints: Kiminori Fujimoto, MD, PhD, Department of Radiology, Kurume University School of Medicine, 67 Asahi-machi, Kurume, 830-0011, Japan (e-mail: kimichan@med.kurume-u.ac.jp).

© 2013 Lippincott Williams & Wilkins, Inc.