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Autogenous and Allogenic Stem Cell Usage in Foot and Ankle Fusions

Bussewitz, Bradly W. DPM; Hyer, Christopher F. DPM, FACFAS

Techniques in Foot & Ankle Surgery:
doi: 10.1097/BTF.0b013e31820b9c26
Special Focus: Bioadjuvant Healing in Foot and Ankle Surgery
Abstract

Orthobiologics are helping surgeons to manipulate healing and reduce delayed unions and nonunions. Surgeons are no longer limited to harvesting the iliac crest to obtain osteoconductive, osteoinductive, and osteogenic materials for grafting purposes. Synthetic substitutes have evolved that have nearly unlimited volume, no associated harvest site morbidity, and may even eclipse the healing capabilities of autogenous grafts. Mesenchymal stem cells, available both by bone marrow aspirate harvest and by commercially available allografts, provide adjuncts to facilitate bone healing in foot and ankle surgery.

Author Information

Orthopedic Foot and Ankle Center, Westerville, OH

Address correspondence and reprint requests to Bradly W. Bussewitz, DPM, Orthopedic Foot and Ankle Center, 300 Polaris Parkway Suite 2000, Westerville, OH 43082. e-mail: ofacresearch@orthofootankle.com.

© 2011 Lippincott Williams & Wilkins, Inc.