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Surgical Laparoscopy, Endoscopy & Percutaneous Techniques:
doi: 10.1097/SLE.0000000000000041
Review Articles

Comparison of the Long-term Results of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy for Morbid Obesity: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Trials

Li, Jian-Fang MD; Lai, Dan-Dan MD; Lin, Zhi-Hong MD; Jiang, Tian-Ye MD; Zhang, Ai-Min PhD; Dai, Jian-Feng MD

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Purpose: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 2 of the most widely used bariatric procedures today, in this meta-analysis, both techniques were compared for evaluating the efficacy and safety of the treatment of morbid obesity.

Materials and Methods: Systematic literature search of Cochrane Controlled Trials Register Databases, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database was performed. Statistical analyses were carried out using RevMan software.

Results: Thirty-two recent studies including 6526 patients in total were included in this meta-analysis. Compared with SG, RYGB had significantly better effect in resolving type 2 diabetes mellitus, hypertension, hypercholesterolemia, gastroesophageal reflux disease, and arthritis. However, RYGB had higher incidence of complications and reoperation, and longer operation time than SG.

Conclusions: RYGB was more effective than SG in the resolution of obesity-related comorbidities, SG was a safer procedure with a reduced rate of complications and reoperation.

© 2014 by Lippincott Williams & Wilkins


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