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Comparison of the Long-term Results of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy for Morbid Obesity: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Trials

Li, Jian-Fang MD; Lai, Dan-Dan MD; Lin, Zhi-Hong MD; Jiang, Tian-Ye MD; Zhang, Ai-Min PhD; Dai, Jian-Feng MD

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques: February 2014 - Volume 24 - Issue 1 - p 1–11
doi: 10.1097/SLE.0000000000000041
Review Articles

Purpose: Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are 2 of the most widely used bariatric procedures today, in this meta-analysis, both techniques were compared for evaluating the efficacy and safety of the treatment of morbid obesity.

Materials and Methods: Systematic literature search of Cochrane Controlled Trials Register Databases, Medline, Embase, ISI databases, and Chinese Biomedical Literature Database was performed. Statistical analyses were carried out using RevMan software.

Results: Thirty-two recent studies including 6526 patients in total were included in this meta-analysis. Compared with SG, RYGB had significantly better effect in resolving type 2 diabetes mellitus, hypertension, hypercholesterolemia, gastroesophageal reflux disease, and arthritis. However, RYGB had higher incidence of complications and reoperation, and longer operation time than SG.

Conclusions: RYGB was more effective than SG in the resolution of obesity-related comorbidities, SG was a safer procedure with a reduced rate of complications and reoperation.

Department of Gastrointestinal Surgery, the First People’s Hospital of Xiaoshan, Hangzhou Normal University, Hangzhou, People’s Republic of China

The authors declare no conflicts of interest.

Reprints: Jian-Fang Li, MD, Department of Gastrointestinal Surgery, the First People’s Hospital of Xiaoshan, Hangzhou Normal University, 199 Shixinnan Road, Hangzhou 311200, People’s Republic of China (e-mail: ljfldd611@163.com).

Received September 8, 2013

Accepted November 1, 2013

© 2014 by Lippincott Williams & Wilkins