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Sexually Transmitted Diseases:
doi: 10.1097/OLQ.0b013e3182787e45
Note

Analytical Specificity and Sensitivity of the APTIMA Combo 2 and APTIMA GC Assays for Detection of Commensal Neisseria Species and Neisseria gonorrhoeae on the Gen-Probe Panther Instrument

Golparian, Daniel MSc*†; Tabrizi, Sepehr N. PhD; Unemo, Magnus PhD*†

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Abstract

Abstract: Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 isolates of nongonococcal Neisseria and related species and 205 gonococcal isolates.

© Copyright 2013 American Sexually Transmitted Diseases Association

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