These 5 cases of atypical inflammatory lymphogranula venereum (LGV) serovar L2b presenting initially with edema and persistent painful ulceration illustrate that clinical manifestations of LGV in the current outbreak in men who have sex with men reflect the influence of both the serovars virulence and the host immune system and are not confined to proctitis. L2b serovar could have a particular high virulence profile, and the need for awareness of LGV as a cause of genital ulceration is crucial.
Primary lymphogranula venereum classically presents as a painless ulceration that heals within 1 week. We report 5 cases of atypical inflammatory lymphogranula venereum serovar L2b presenting initially with edema and persistent painful ulceration.
From the *Dermatologie et Vénéréologie, Hopital Saint Louis, Universités Bobigny, Paris, France; †Dermatologie et Vénéréologie, Hopital Hammoud, Beyrouth, Liban; ‡Centre National de Référence des Chlamydiae et des Mycoplasma, Université de Bordeaux, Bordeaux ; and §Dermatologie et Vénéréologie, Hopital Saint Louis, Paris, France
Conflict of interest and sources of funding: None declared.
Correspondence: Roger Haber, MD, Dermatologie et Vénéréologie, Hopital Saint Louis, Universités Bobigny-Paris 13, 1 Avenue Claude Vellefaux, 75010, Paris, France. E-mail: firstname.lastname@example.org.
Received for publication November 17, 2016, and accepted January 20, 2017.