Intracerebral and Spinal Cord Syphilitic Gummata in an HIV-Negative Man: A Case Report

Dhasmana, Divya MRCP; Joshi, Jaishree MRCOG; Manavi, Kaveh MD, FRCP

Sexually Transmitted Diseases:
doi: 10.1097/01.OLQ.0000430779.41370.ba
Note
Abstract

Abstract: We present a case of an HIV-negative individual who presented with worsening central and peripheral neurological symptoms and signs. Clinical, serological, histopathological, and radiological features were in keeping with concurrent cerebral and spinal cord syphilitic gummata, a tertiary manifestation of syphilis. Clinical improvement occurred after treatment of neurosyphilis.

In Brief

A case report of an HIV-negative individual with concurrent intracerebral and spinal cord gummata showing clinical response to treatment of neurosyphilis.

Author Information

From the Department of Sexual Health and HIV, Whittall Street Clinic, University Hospitals Birmingham NHS Foundation Trust, Whittall Street, Birmingham, UK

The authors thank Rachael McGrath for the translation of the French paper by El Quessar et al. (J Neuroradiol. 2000; 27(3): 207:210).

Source of funding: Nil.

Conflict of interest: None declared.

Correspondence: Divya Dhasmana, MRCP, Department of Sexual Health and HIV, Whittall Street Clinic, University Hospitals Birmingham NHS Foundation Trust, Whittall Street, Birmingham, B6 4DH, United Kingdom. E-mail: divya.dhasmana@nhs.net.

Received for publication December 16, 2012; and accepted April 11, 2013.

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