Sexually Transmitted Diseases

Skip Navigation LinksHome > April 2013 - Volume 40 - Issue 4 > An Integrated City-Driven Perinatal HIV Prevention Program C...
Sexually Transmitted Diseases:
doi: 10.1097/OLQ.0b013e3182805186
Original Study

An Integrated City-Driven Perinatal HIV Prevention Program Covering 1.8 Million Pregnant Women in Shenzhen, China, 2000 to 2010

Song, Junmin MD*; Feng, Tiejian MD; Bulterys, Marc MD, PhD; Zhang, Dan MD§; Korhonen, Christine MPH; Shi, Xiangdong MD*; Wang, Xiaohui PhD*; Cheng, Jinquan PhD*; Chen, Lin MD*; Ma, Hanwu MD*

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Background: Despite the scale-up of prevention of mother-to-child transmission (PMTCT) programs worldwide, the translation from research studies into public health policy has been slow. This report details the experiences of a city-driven PMTCT program in China using existing health resources.

Methods: The PMTCT program was devised to hospital based and city-wide. It achieves full use of available resources: the local Centers for Disease Control and Prevention, the Infectious Disease Hospital, Maternal and Child Health Hospitals, and all qualified comprehensive hospitals.

Results: From 2000 to 2010, 1,843,122 pregnant women attended prenatal care or labor and delivery services. Overall, 97.4% received pretest HIV counseling, and 96.2% were tested for HIV. Among the 81.1% (1,495,122) of women who attended prenatal clinics, 97.2% (1,452,753) received pretest counseling and 95.7% (1,430,799) were tested for HIV. Among the 18.9% (348,000) of women with an undocumented HIV status at labor and delivery, 98.6% (343,038) received pretest counseling, and 98.1% (341,371) were tested for HIV. In total, 229 women were determined HIV positive for a prevalence of 1.3 per 10,000 pregnant women. Among the 107 HIV-infected women who carried to delivery, 87.9% received antiretroviral prophylaxis for themselves and their infants. Among the 58 women who were identified HIV positive at labor, 10.3% of mothers and 72.4% of infants received antiretroviral prophylaxis. The estimated mother-to-child transmission rate was 5.3% (95% confidence interval, 2.2%–10.7%).

Conclusions: With appropriate integration, existing health care resources are adequate for a comprehensive city-driven PMTCT program in an area with a low HIV prevalence.

© Copyright 2013 American Sexually Transmitted Diseases Association


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