Sexually Transmitted Diseases

Skip Navigation LinksHome > February 2012 - Volume 39 - Issue 2 > Chlamydia trachomatis Trends in the United States Among Pers...
Sexually Transmitted Diseases:
doi: 10.1097/OLQ.0b013e31823e2ff7
Original Study

Chlamydia trachomatis Trends in the United States Among Persons 14 to 39 Years of Age, 1999–2008

Datta, S. Deblina MD*; Torrone, Elizabeth PhD, MSPH*,†; Kruszon-Moran, Deanna ScM; Berman, Stuart MD, ScM*; Johnson, Robert MD, MPH*; Satterwhite, Catherine L. PhD, MSPH, MPH*; Papp, John PhD*; Weinstock, Hillard MD, MPH*

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Background: We report the first population-based assessment of national trends in chlamydia prevalence in the United States.

Methods: We investigated trends in chlamydia prevalence in representative samples of the US population aged 14 to 39 years using data from five 2-year survey cycles of the National Health and Nutrition Examination Survey from 1999 to 2008. Prevalence estimates and 95% confidence intervals (CI) are reported stratified by age, gender, and race/ethnicity. Percent change in prevalence over this time period was estimated from regression models.

Results: In the 2007–2008 cycle, chlamydia prevalence among participants aged 14 to 39 years was 1.6% (95% CI: 1.1%–2.4%). Prevalence was higher among females (2.2%, 95% CI: 1.4%–3.4%) than males (1.1%, 95% CI: 0.7%–1.7%). Prevalence among non-Hispanic black persons was 6.7% (95% CI: 4.6%–9.9%) and was 2.5% (95% CI: 1.6%–3.8%) among adolescents aged 14 to 19 years. Over the five 2-year cycles, there was an estimated 40% reduction (95% CI: 8%–61%) in prevalence among participants aged 14 to 39 years. Decreases in prevalence were notable in men (53% reduction, 95% CI: 19%–72%), adolescents aged 14 to 19 years (48% reduction, 95% CI: 11%–70%), and adolescent non-Hispanic black persons (45%, reduction, 95% CI: 4%–70%). There was no change in prevalence among females aged 14 to 25 years, the population targeted for routine annual screening.

Conclusions: On the basis of population estimates of chlamydia prevalence, the overall chlamydia burden in the United States decreased from 1999 to 2008. However, there remains a need to reduce prevalence in populations most at risk and to reduce racial disparities.

© Copyright 2012 American Sexually Transmitted Diseases Association


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