Sexually Transmitted Diseases

Skip Navigation LinksHome > January 2010 - Volume 37 - Issue 1 > Effect of Menses on Clearance of Y-Chromosome in Vaginal Flu...
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Sexually Transmitted Diseases:
doi: 10.1097/OLQ.0b013e3181b5f15d
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Effect of Menses on Clearance of Y-Chromosome in Vaginal Fluid: Implications for a Biomarker of Recent Sexual Activity

Brotman, Rebecca M. PHD, MPH*; Melendez, Johan H. MS†; Smith, Tukisa D. MS†; Galai, Noya PHD‡§; Zenilman, Jonathan M. MD†

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Abstract

Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.

© Copyright 2010 American Sexually Transmitted Diseases Association

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