Sexually Transmitted Diseases

Skip Navigation LinksHome > February 2007 - Volume 34 - Issue 2 > Screening HIV-Infected Women for Cervical Cancer in Thailand...
Sexually Transmitted Diseases:
doi: 10.1097/01.olq.0000222716.17186.9f
Article

Screening HIV-Infected Women for Cervical Cancer in Thailand: Findings From a Demonstration Project

Sirivongrangson, Pachara MD*; Bollen, Liesbeth J. M. MD, PhD†; Chaovavanich, Achara MD‡; Suksripanich, Orapin BSc†; Virapat, Pongsri RN†; Tunthanathip, Preecha MD‡; Ausavapipit, Jarurnsook RN‡; Lokpichat, Somchai MSc*; Siangphoe, Umaporn MSc†; Jirarojwat, Naiyana RN*; Pobkeeree, Vallerut BSc, MA†; Supawitkul, Somsak MD†; Tappero, Jordan W. MD, MPH†§; Levine, William C. MD, MSc†§

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Abstract

Objectives: Although cervical cancer is an AIDS-defining illness, few HIV-infected women are routinely screened for cervical cancer in Thailand. We screened HIV-infected women for cervical cancer as a component of HIV care and assessed high-risk human papillomavirus (HPV) and cervical cancer prevalence.

Methods: From July 2003 through February 2004, HIV-infected women attending either an infectious disease clinic or a sexually transmitted infection (STI) clinic in Bangkok were tested for high-risk HPV types by Hybrid Capture 2 and screened for cervical cancer by Pap test; those with abnormal cervical cytology were referred for diagnosis and treatment.

Results: Two hundred ten HIV-infected women at an infectious disease clinic (n = 150) and an STI clinic (n = 60) received cervical cancer screening. The high-risk HPV prevalence was 38.6% and the prevalence of abnormal cervical cytology was 20.4%. Abnormal cervical cytology and high-risk HPV detection were associated (P < 0.001). We received pathology reports for 23 (53.5%) of 43 women, including all those with a Pap test showing high-grade squamous intraepithelial lesions; the cervical cancer prevalence was 1.9% (4 of 210; 95% confidence interval, 0.5–4.8%).

Conclusion: The estimated prevalence of high-risk HPV and cervical cancer among HIV-infected women in Thailand was high. This emphasizes the need to integrate cervical cancer screening into HIV care.

© Copyright 2007 American Sexually Transmitted Diseases Association

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