Sexually Transmitted Diseases

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Sexually Transmitted Diseases:
Commentary

HIV Superinfection in the Era of Increased Sexual Risk-Taking

Blackard, Jason T. PhD*; Mayer, Kenneth H. MD†

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Abstract

Recent reports have documented increases in unprotected intercourse (UI) and sexually transmitted diseases (STDs) among men who have sex with men (MSM) and other at-risk populations. A further consequence of persons living with HIV engaging in unprotected intercourse or shared parenteral exposures with seroconcordant partners is HIV recombination and superinfection, possibly with a drug-resistant or more pathogenic virus. The epidemiologic, clinical, and therapeutic implications of recent case reports confirming superinfection in persons living with HIV, as well as research priorities aimed at providing a more thorough understanding of the consequences of unprotected sex among HIV-infected people, are explored here.

© Copyright 2004 American Sexually Transmitted Diseases Association

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