Study Design. Retrospective case series study.
Objective. To clarify the results of a long-term (30 yr) follow-up study of artificial disk replacement (ADR) for the treatment of cervical disk disease.
Summary of Background Data. The use of the ADR procedure has become widespread during the past 10 years. Its purpose is to preserve motion of the functional spinal unit. However, the long-term results are unknown.
Methods. Thirty-seven patients underwent ADR between 1980 and 1985 in the Department of Orthopedic Surgery, Changzheng Hospital. Twenty-one patients, who had a complete follow-up, underwent radiographical evaluation to detect heterotopic ossification, segmental range of motion, and adjacent segmental changes. In addition, patients were asked to complete preoperative and postoperative visual analogue scale, neck disability index, and 36-Item Short Form Health Survey questionnaires for evaluation of neurological function and pain severity. The occurrence of adverse events and reoperations was examined and these parameters served as indicators of device safety.
Results. Twenty-one patients had a complete follow-up average of 30 years (range, 28–33 yr). The 21 patients reported improvement of the preoperative neurological symptoms. At the last follow-up, the motion was preserved in 19 of the 26 (73%) segments. None of the patients presented with symptomatic adjacent segment degeneration. Nineteen of the 21 (90%) patients presented heterotopic ossification, but none of them underwent reoperation correlated with heterotopic ossification. No device-related adverse events were recorded.
Conclusions. Artificial disk replacement to treat degenerative cervical disk disorders can preserve the motion of the spinal unit in young patients, which fulfills the original purpose of its design. We consider this procedure is worth applying in such a population. However, whether this procedure can prevent adjacent segment degeneration will require further investigation.
Level of Evidence: 2
A 30 years' follow-up study showed that artificial disc replacement to treat degenerative cervical disc disorders could preserve the motion of the spinal unit, which fulfilled the original purpose of its design. Heterotopic ossification and adjacent segment degeneration could be seen, but it did not affect the outcome.
From the Department of Orthopedic Surgery, Changzheng Hospital, Shanghai, China.
Address correspondence and reprint requests to Xuhua Lu, MD, Department of Orthopedic Surgery, Changzheng Hospital, 415 Feng Yang Rd, Shanghai 200003, China, E-mail: firstname.lastname@example.org, co-corresponding author: Wen Yuan, MD, E-mail: email@example.com
Acknowledgment date: February 4, 2014. Revision date: May 4, 2014. Acceptance date: May 30, 2014.
The manuscript submitted does not contain information about medical device(s)/drug(s).
The device(s)/drug(s) that is/are the subject of this manuscript is/are not FDA-approved for this indication and is/are not commercially available in the United States.
No funds were received in support of this work.
No relevant financial activities outside the submitted work.