Skip Navigation LinksHome > May 15, 2014 - Volume 39 - Issue 11 > Long-term Outcomes of 2-Level Total Disc Replacement Using P...
Text sizing:
doi: 10.1097/BRS.0000000000000148

Long-term Outcomes of 2-Level Total Disc Replacement Using ProDisc-L: Nine- to 10-Year Follow-up

Balderston, Jessica R. BS*; Gertz, Zachary M. MD; McIntosh, Theresa CRNP; Balderston, Richard A. MD

Collapse Box


Study Design. A prospective clinical data analysis.

Objective. To determine the long-term clinical success of 2-level total disc replacement (TDR) in patients with degenerative disc disease.

Summary of Background Data. Early successful clinical results of 2-level TDR have been reported. Few studies exist that have described this procedure's durability in the long term.

Methods. Fifteen patients underwent 2-level lumbar TDR with the ProDisc-L as part of a randomized trial, 13 of whom were available for follow-up. The patients were assessed preoperatively and at 2 years, 5 years, and more than 9 years postoperatively using visual Oswestry Disability Index. At the last follow-up visit, 2 additional questions were asked: satisfaction with surgery and willingness to undergo the same treatment. Finally, clinical success was assessed using a previously described definition.

Results. Mean follow-up time was 9.6 years (range, 9.2–10.3 yr). Postoperatively there was a significant improvement in Oswestry Disability Index score from baseline (70.0 vs. 15.7 at 2 yr, P = 0.002) that remained unchanged during the period of follow-up (19.8 at 5 yr, P = 0.003 and 12.9 at 9–10 yr, P = 0.002). Ninety-two percent of patients were “satisfied” or “somewhat satisfied” with treatment and the same number would undergo treatment again. Eighty-five percent of patients achieved clinical success.

Conclusion. This prospective study demonstrates the durable clinical success of 2-level lumbar TDR as assessed at more than 9 years postoperatively.

Level of Evidence: 4

© 2014 by Lippincott Williams & Wilkins

Follow Us!



Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.