Study Design. A questionnaire-based identification of adolescent idiopathic scoliosis (AIS) patients and measure of Short Form-12 (SF-12) in a big twin-cohort.
Objective. The purpose was to study the effect that AIS has on the health-related quality of life in the patients.
Summary of Background Data. The effect of AIS on the perceived health status is still unclear.
Methods. All 46,418 twins registered in the Danish Twin Registry born between 1931 and 1982 were sent a questionnaire including SF-12. The questionnaire was returned by 34,944 (75.3%) twins representing 23,204 pairs.
Results. A group of 220 subjects considered to have AIS was identified corresponding to a prevalence of 1.05%. In this group, the SF-12 could be calculated in 187 twins.
Conclusion. We found the perceived both mental and physical health status from SF-12 to be moderately but significantly worse than in controls. Approximately 75% of the twins with AIS reported to have the same or a better health than their twin- and age-matched peers.
The effect of adolescent idiopathic scoliosis on the perceived health status is still unclear. A total of 46,418 twins were sent a questionnaire including Short Form-12. We found the perceived both mental and physical health status from Short Form-12 to be moderately but significantly worse in twins with adolescent idiopathic scoliosis than in controls.
From the *Spine Section, Department of Orthopaedic Surgery, Sygehus Lillebaelt, Denmark; †Spine Section, Hamlet Private Hospital, Denmark; and ‡The Danish Twin Registry, Institute of Public Health, University of Southern Denmark, Denmark.
Acknowledgment date: March 6, 2007. Revision date: June 21, 2009. Acceptance date: August 10, 2009.
The manuscript submitted does not contain information about medical device(s)/drug(s).
No funds were received in support of this work. No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.
Address correspondence and reprint requests to Mikkel Andersen, MD, Spine Section, Department of Orthopeadic Surgery, Sygehus Lillebaelt, Kabbeltoft 25, 7100 Vejle, Denmark; E-mail: firstname.lastname@example.org