Skip Navigation LinksHome > September 15, 2000 - Volume 25 - Issue 18 > Genetics of Familial Idiopathic Scoliosis
Spine Update

Genetics of Familial Idiopathic Scoliosis

Hadley Miller, Nancy MD

Collapse Box


The etiology of familial idiopathic scoliosis remains in question. The role of genetic factors in the development of this disorder has been well-documented; however, reports of the specific mode of genetic inheritance are inconclusive. These facts, combined with the phenotypic variability of this disorder, suggest that the genetic expression if idiopathic scoliosis may be dependent upon multiple factors and genetic interactions. Strategies to resolve the complex nature of this condition include genome-wide scanning of one extensive family or, alternatively, a well-characterized population of families affected with idiopathic scoliosis.

© 2000 Lippincott Williams & Wilkins, Inc.

Follow Us!



Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.