The case of a 57-year-old male with a history significant for myeloproliferative disease, chronic renal failure, hypertension, and prostate cancer is described. His complete blood count was remarkable for neutrophilia and, notably, eosinophilia. Subsequent to two syncopal episodes, a transthoracic echocardiogram was performed as part of the workup, which showed an unusual calcified mass in the left ventricular apical region but separate from the apical myocardium, with normal left ventricular systolic function. A transesophageal echocardiogram and computed tomography of the chest confirmed the presence of extensive calcification in the left ventricle of unusual location and shape. This patient probably had Loeffler endocarditis related to myeloproliferative disorder, complicated by calcification of the endocardial sclerotic lesions.
* Loeffler endocarditis causing calcification is known to occur in patients with chronic prolonged eosinophilia.
* Cardiac calcification of an unusual configuration and location was seen on echocardiography and computed tomography.
* Other causes of cardiac calcification were considered and thought very unlikely; ventricular systolic function and wall motion were normal on echocardiography.