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Skip Navigation LinksHome > August 2005 - Volume 98 - Issue 8 > Retention of Extended Release Nifedipine Capsules in a Patie...
Southern Medical Journal:
doi: 10.1097/01.smj.0000173085.76821.11
Case Report

Retention of Extended Release Nifedipine Capsules in a Patient with Enteric Stricture Causing Recurrent Small Bowel Obstruction

Yeen, Wing C. MD, MBA; Willis, Irwin H. MD, FACS

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Abstract

Medication bezoars from extended release medication have been reported in the literature. This has become an increasing phenomenon with the popularity of extended release formulations, which aim to increase therapeutic compliance. We report on a patient who experienced recurrent bouts of small bowel obstruction, necessitating surgical exploration.

Key Points

* Pharmacobezoars is an increasing phenomenon with the popularity of extended release formulation of medication aiming to increase therapeutic compliance.

* Presenting symptoms due to intermittent or complete obstruction include weight loss, nausea, vomiting and early satiety.

* Bezoars may form as a result of GI surgery, pathologic or iatrogenic narrowing of the GI anatomy or slowed GI motility.

* Physicians should be aware of the potential complications in high risk patients.

* A detailed history and physical examination may prevent pharmacobezoars in those with prior peptic ulcer disease, cancer, or other conditions potentially leading to narrowing of the gastrointestinal lumen.

© 2005 Southern Medical Association

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