Skip Navigation LinksHome > January 2016 - Volume 27 - Issue 1 > AIDS-related malignancies
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Reviews in Medical Microbiology:
doi: 10.1097/MRM.0000000000000055
Virology

AIDS-related malignancies

Qadir, Muhammad I.a; Abbas, Khizarb; Qadeer, Kahkashanb; Abid, Ammanb

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Abstract

There is a high risk of developing malignancies in persons infected with HIV. The most common AIDS-related cancer is Kaposi's sarcoma, which is caused by Kaposi's sarcoma-linked herpesvirus. Others are invasive cervical cancer and non-Hodgkin's lymphoma caused by human papillomavirus and Epstein–Barr virus, respectively. Among the chemotherapeutic agents, pegylated liposomal doxorubicin is an effective therapy for patients with HIV-linked Kaposi's sarcoma. There is also a chance of developing non-AIDS-related cancers, for example, Hodgkin's disease and multiple myeloma. Use of highly active antiretroviral therapy is very important for controlling the malignancies, as well as the occurrence of long-term infections and prognosis.

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