Purpose: To describe the first reported case of endophthalmitis after 20-gauge vitrectomy caused by Serratia marcescens.
Methods: Retrospective case report.
Results: An 86-year-old woman underwent a standard 20-gauge vitrectomy for repair of a chronic rhegmatogenous retinal detachment. All sclerotomies were sutured at the completion of the case. Within 2 days after surgery, she developed severe endophthalmitis. A bacterial culture of her aqueous sample was positive for S. marcescens. Despite the culture-demonstrated sensitivity of this organism to the antibiotics given intravitreally, systemically, and topically to treat this infection, her condition deteriorated, and she developed panophthalmitis, orbital cellulitis, a corneal ulcer, and eventual no light perception vision.
Conclusions: This is the first reported case of S. marcescens endophthalmitis after vitrectomy surgery. Endophthalmitis caused by S. marcescens has a poor visual prognosis and may show an in vivo clinical resistance to antibiotic therapy regardless of in vitro culture sensitivities.
The authors describe the first reported case of endophthalmitis after 20-gauge vitrectomy caused by Serratia marcescens. S. marcescens endophthalmitis has a poor visual prognosis and may show an in vivo clinical resistance to antibiotic therapy regardless of in vitro culture sensitivities.
From the *Associated Retinal Consultants, Royal Oak; and †Michigan State College of Human Medicine, East Lansing, Michigan.
The authors have no financial interest.
Reprint requests: David T. Goldenberg, MD, Associated Retinal Consultants, 3535 W. 13 Mile Road, Suite 344, Royal Oak, MI 48073; e-mail: firstname.lastname@example.org