Purpose: To evaluate the incidence rates of iatrogenic retinal breaks in eyes that underwent 25-gauge vitrectomy under air compared with 25-gauge standard vitrectomy for idiopathic macular holes or idiopathic epiretinal membranes.
Methods: In this retrospective, comparative interventional study, 435 eyes were enrolled. In all patients after core vitrectomy and epiretinal/inner limiting membrane peeling, complete vitrectomy of the base was performed, respectively under air (air group) or under fluid infusion (standard group).
Results: The number of eyes with iatrogenic retinal breaks was significantly lower in the air group than in standard group (4/197 and 16/238, 2% and 7%, respectively; P = 0.035). A postoperative retinal detachment developed in 2 eyes (1%) in the standard group, and in no eyes of the air group (0%). Factors related to the occurrence of retinal breaks were surgically induced posterior vitreous detachment (P = 0.006), standard vitrectomy (P = 0.023), and surgery for macular hole (P = 0.030).
Conclusion: The 25-gauge vitrectomy under air is associated with a lower incidence rate of retinal breaks compared with the standard 25-gauge vitrectomy.
This study showed that the 25-gauge vitrectomy under air significantly reduces the incidence of iatrogenic retinal breaks compared with the standard 25-gauge vitrectomy in eyes undergoing surgery for macular disease.
*Department of Ophthalmology, University of Catania, Catania, Italy;
†Department of Ophthalmology, Santa Chiara Hospital, Pisa, Italy; and
‡Department of Ophthalmology, University of Ancona, Ancona, Italy.
Reprint requests: Michele Reibaldi, MD, PhD, Department of Ophthalmology, University of Catania, Via S. Sofia 78, Catania 95124, Italy; e-mail: firstname.lastname@example.org
S. Rizzo is a paid consultant for Alcon. The other authors have no financial/conflicting interests to disclose.