Institutional members access full text with Ovid®

Share this article on:

ASSOCIATION BETWEEN RETINAL VENULAR DILATION AND SEROUS RETINAL DETACHMENT IN DIABETIC MACULAR EDEMA

Muraoka, Yuki MD*; Murakami, Tomoaki MD*; Nishijima, Kazuaki MD*,†; Akagi, Tadamichi MD*; Uji, Akihito MD*; Horii, Takahiro MD*; Ueda-Arakawa, Naoko MD*; Yoshikawa, Munemitsu MD*; Tsujikawa, Akitaka MD*; Yoshimura, Nagahisa MD*

doi: 10.1097/IAE.0b013e3182a48732
Original Study

Purpose: To study the relationship between retinal vessel diameter and qualitative and quantitative evaluations on spectral-domain optical coherence tomography in patients with diabetic macular edema.

Methods: One hundred and eight consecutive eyes of 80 patients, with clinically significant macular edema underwent optical coherence tomography and color fundus photography. The authors evaluated the retinal thickness of the Early Treatment Diabetic Retinopathy Study grid and foveal pathomorphologies including cystoid macular edema and serous retinal detachment on the optical coherence tomography images. The diameters of the superotemporal or inferotemporal retinal vessels originating from the optic disk were measured using a computer-assisted technique.

Results: The mean diameters of the superotemporal and inferotemporal venules were larger in eyes with diabetic macular edema than in healthy eyes. The mean diameter of the temporal venules but not the arterioles was associated with perifoveal thickening in the inferior subfield in eyes with diabetic macular edema (P = 0.014). Although the retinal thickening in the central subfield was not correlated with the diameters of the retinal vessels, eyes with foveal serous retinal detachment had larger mean diameters of superotemporal and inferotemporal venules than those without serous retinal detachment (P < 0.001).

Conclusion: The mean diameters of the superotemporal and inferotemporal venules were significantly associated with foveal serous retinal detachment in diabetic macular edema.

The larger mean diameters of the superotemporal and inferotemporal venules but not the arterioles are associated with serous retinal detachment at the fovea in diabetic macular edema.

*Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan; and

Nishijima Eye Clinic, Kyoto, Japan.

Reprint requests: Tomoaki Murakami, MD, Department of Ophthalmology, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawaharacho, Sakyo, Kyoto 606-8507, Japan; e-mail: mutomo@kuhp.kyoto-u.ac.jp

None of the authors have any financial/conflicting interests to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.retinajournal.com).

© 2014 by Ophthalmic Communications Society, Inc.