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ASSESSMENT OF VISION-RELATED QUALITY OF LIFE IN PATIENTS WITH CENTRAL RETINAL ARTERY OCCLUSION

Weger, Martin MD*; Pichler, Tamara MSc*; Franke, Gabriele H. PhD; Haas, Anton MD*; Thaler, Herbert V. MD*; Kraigher-Krainer, Nora*; Groselj-Strele, Andrea MSc; Wedrich, Andreas MD*; Rabensteiner, Dieter F. MD*

doi: 10.1097/IAE.0b013e3182a0e42e
Original Study

Background: Central retinal artery occlusion (CRAO) is a major cause for severe visual impairment. Its effect on vision-related quality of life has not yet been determined. The purpose of the present study was thus to assess vision-related quality of life in patients with CRAO using the 39-item National Eye Institute Visual Function Questionnaire.

Methods: The case–control study comprised 26 patients with unilateral CRAO and a control group consisting of 26 control subjects, matched for age and sex. Vision-related quality of life was measured using the 39-item National Eye Institute Visual Function Questionnaire.

Results: After Bonferroni correction, the median 39-item National Eye Institute Visual Function Questionnaire composite score was significantly lower in patients with CRAO than in those in the control group (Pcorr < 0.001). Patients with CRAO showed significantly lower median scores in 9 of 12 subscales: general vision (Pcorr < 0.001), peripheral vision (Pcorr < 0.001), difficulties with near-vision activities (Pcorr < 0.001), difficulties with distance-vision activities (Pcorr < 0.001), role difficulties as a result of vision problems (Pcorr < 0.001), dependency on others because of vision problems (Pcorr < 0.001), limitations in social functioning because of vision problems (Pcorr < 0.001), mental health symptoms because of vision problems (Pcorr < 0.001), and general health (Pcorr = 0.008).

Conclusion: Our data suggest that vision-related quality of life is reduced in patients with CRAO.

Using the 39-item National Eye Institute Visual Function Questionnaire, patients with unilateral central retinal artery occlusion were shown to have significantly reduced vision-related quality of life scores.

*Department of Ophthalmology, Medical University of Graz, Graz, Austria;

Department of Rehabilitation Psychology, Applied Human Sciences, University of Applied Sciences Magdeburg-Stendal, Stendal, Germany; and

Center for Medical Research, Office of Biostatistics, Medical University of Graz, Graz, Austria.

Reprint requests: Martin Weger, MD, Department of Ophthalmology, Medical University of Graz, Auenbruggerplatz 4, 8036 Graz, Austria; e-mail: martin.weger@medunigraz.at

None of the authors have any financial/conflicting interests to disclose.

© 2014 by Ophthalmic Communications Society, Inc.