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CHANGING PROFILE OF ORGANISMS CAUSING SCLERAL BUCKLE INFECTIONS: A Clinico-microbiological Case Series

Mohan, Neha MS*; Kar, Sarita MSc; Padhi, Tapas Ranjan MS*; Basu, Soumyava MS*; Sharma, Savitri MD; Das, Tara Prasad MD*

doi: 10.1097/IAE.0b013e3182979e4a
Original Study

Purpose: To study the microbiological spectrum and in vitro susceptibility of bacterial isolates from explanted scleral buckles and to correlate clinical presentation to the causative agent.

Method: Medical records of patients who underwent buckle explantation from July 2007 to May 2012 were reviewed retrospectively. Clinical features and microbiological profile were noted and correlated.

Results: Twenty of 24 buckles (83.33%) from 24 patients grew 21 isolates. Isolates included 6 acid-fast bacilli (28.57%; atypical mycobacteria = 5, Nocardia asteroides = 1), 5 gram-positive bacilli (23.8%; Corynebacterium spp. = 4, Bacillus sp. = 1), 4 gram-positive cocci (19.0%; Staphylococcus spp. = 4), 2 gram-negative bacilli (9.5%; Pseudomonas aeruginosa = 2), and 4 fungi (19.0%; Aspergillus spp. = 3, Paecilomyces sp. = 1). Acid-fast bacilli and gram-negative bacilli were sensitive to amikacin and gram-positive bacilli and gram-positive cocci to vancomycin. Buckle exposure within 2 years of primary surgery tended to be noninfective (P = 0.06). Fungal or mycobacterial infections were more symptomatic than those with Corynebacterium species. Results of microscopic examination of conjunctival swab in 5 of 7 eyes (71.4%) were consistent with culture of conjunctival swab and explanted buckles.

Conclusion: Clinical features and microscopic examination of conjunctival swab may give a lead toward the causative organism in suspected buckle infections. Based on these leads, vancomycin and amikacin may be used as the initial empirical therapy.

Relative distribution of microorganisms causing scleral buckle infections was different from previously reported series, although the antibiotic susceptibility pattern appeared similar. Clinical features may hint and microscopic examination of conjunctival swab can identify the causative organism and may help initiate appropriate empirical therapy to prevent complications like endophthalmitis.

*Retina Vitreous Service, and

Ocular Microbiology Service, L V Prasad Eye Institute, Bhubaneswar, India.

Reprint requests: Savitri Sharma, MD, Ocular Microbiology Service, L V Prasad Eye Institute, Bhubaneswar 751024, Orissa, India; e-mail: savitri@lvpei.org

Supported by the Hyderabad Eye Research Foundation, Hyderabad, India.

None of the authors have any conflicting interests to disclose.

© 2014 by Ophthalmic Communications Society, Inc.