Skip Navigation LinksHome > April 2012 - Volume 32 - Issue 4 > FACTORS AFFECTING PATIENTS' PAIN INTENSITY DURING IN OFFICE...
Retina:
doi: 10.1097/IAE.0b013e3182252ad3
Original Study

FACTORS AFFECTING PATIENTS' PAIN INTENSITY DURING IN OFFICE INTRAVITREAL INJECTION PROCEDURE

Rifkin, Lana MD; Schaal, Shlomit MD, PhD

Collapse Box

Abstract

Purpose: To determine factors associated with patients' comfort during routine in-office intravitreal injection.

Methods: Sixty patients receiving intravitreal injections over 15 months for macular edema because of diabetes, age-related macular degeneration, or retinal vein occlusion who were randomized into 3 groups to receive 1 of 3 commonly used forms of anesthesia—TetraVisc, proparacaine HCl, or tetracaine HCl—before receiving intravitreal injection were studied. Fifteen minutes after injection, patients were asked to rate their pain from 0 (no pain/no distress) to 10 (agonizing pain/unbearable distress) using a Visual Analog Pain score survey. Self-reported pain scores were stratified by age, gender, diagnosis, injection number, substance injected, needle gauge, and visual acuity improvement.

Results: Intravitreal injection was associated with low pain scores. Patients receiving tetracaine reported a statistically significant lower pain score (3.05 ± 2.01) than patients receiving proparacaine (3.17 ± 2.18) or TetraVisc (3.3 9± 2.26; P < 0.01). Other important factors influencing pain score significantly (P < 0.01) included improved vision from previous injection, female sex, and age >65 years. Pain scores decreased with each consecutive injection.

Conclusion: Pain associated with intravitreal injection is generally mild, and may be associated with epidemiologic and environmental factors.

© The Ophthalmic Communications Society, Inc.

Login

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.