Psychiatric Genetics

Skip Navigation LinksHome > April 2011 - Volume 21 - Issue 2 > Database of genetic studies of bipolar disorder
Text sizing:
Psychiatric Genetics:
doi: 10.1097/YPG.0b013e328341a346
Review Articles

Database of genetic studies of bipolar disorder

Piletz, John E.a; Zhang, Xiaotongb; Ranade, Rajdeepa; Liu, Chunyub

Collapse Box


This study describes the construction and preliminary analysis of a database of summary level genetic findings for bipolar disorder from the literature. The database is available for noncommercial use at This may be the first complete collection of published gene-specific linkage and association findings on bipolar disorder, including genome-wide association studies. Both the positive and negative findings have been incorporated so that the statistical and contextual significance of each finding may be compared semi-quantitatively and qualitatively across studies of mixed technologies. The database is appropriate for searching a literature populated by mainly underpowered studies, and if ‘hits’ are viewed as tentative knowledge for future hypothesis generation. It can serve as the basis for a mega-analysis of candidate genes. Herein, we discuss the most robust and best replicated gene findings to date in a contextual manner.

© 2011 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.