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Journal of Psychiatric Practice:
doi: 10.1097/01.pra.0000438188.66735.68
COLUMNS: Psychopharmacology

Outliers on the Dose-Response Curve: If the Problem Is Not Concentration, Then What?

PRESKORN, SHELDON H. MD

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Abstract

This column addresses the two primary reasons some patients do not respond as usual to a medication. Such patients may not benefit either because they are uniquely sensitive to the adverse effects of the drug and/or because the drug does not work on the correct mechanism of action to treat the illness. This column explains and reviews these concepts and provides a rationale for using such information prospectively to increase the likelihood of an optimal outcome with the prescribed treatment. (Journal of Psychiatric Practice 2013;19:490–494)

Copyright © 2013 Lippincott Williams & Wilkins Inc.

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