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Journal of Psychiatric Practice:
doi: 10.1097/01.pra.0000413279.95843.b5
Clinical Case Discussion

Hyperprolactinemia in a Patient with a Pituitary Adenoma Receiving Antipsychotic Drug Therapy

CARROLL, RICHARD W. MB ChB*; CHRISTODOULOU, POLYXENI MB ChB; BAYNES, KEVIN C. R. MBBS PhD; KAHN, DAVID A. MD

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Abstract

Hyperprolactinemia is a common consequence of treatment with an antipsychotic medication. It can result in hypogonadism due to the inhibitory effect of elevated prolactin levels on the hypothalamic-pituitary-gonadal hormonal axis. We present a case of hypogonadism secondary to hyperprolactinemia in a patient taking antipsychotic medication, with radiological evidence of a pituitary microadenoma. The relevance and investigation of hyperprolactinemia in patients being treated with antipsychotic medications are discussed. (Journal of Psychiatric Practice 2012;18:126–129)

© 2012 Lippincott Williams & Wilkins, Inc.

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