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Psychotropic Drugs in Pregnancy and Lactation


Journal of Psychiatric Practice:
Winner of Resident Paper Award 2004-2005

The management of psychotropic medications during pregnancy and lactation involves a difficult and complex decision for both patient and provider, particularly due to the many unknown effects medication may have on the infant. Available studies concerning use of psychotropic medications in pregnant and lactating women are limited and there are no universal guidelines. This article reviews the literature on the use of psychotropic drugs, including antidepressants, mood stabilizers, antipsychotics, and benzodiazepines, in pregnant and breast-feeding women and presents relevant data on teratogenic effects, neonatal toxicity, perinatal syndromes, and neurobehavioral sequelae.

Author Information

JAIN: Walter Reed Army Medical Center; LACY: Malcolm Grow Medical Center.

Please send correspondence and reprint requests to: Audrey E. Jain, DO, Walter Reed Army Medical Center, Department of Psychiatry, 6900 Georgia Avenue NW, Washington, DC 20307-5001.

© 2005 Lippincott Williams & Wilkins, Inc.