This is the first report of acellular dermis presenting as a new breast mass and represents an important finding, as a new mass in a patient with a history of breast cancer generates significant patient and patient family anxiety, and is associated with increased risks related to proper evaluation of the mass.
The intrinsic nature of acellular dermis lends itself to the development of masses and inflammatory nodules within the breast as a result of a paucity of significant subcutaneous fat in this area, along with relatively thin mastectomy skin flaps.
This is an important consideration for patients undergoing immediate reconstruction with acellular dermis. Patients should be informed that natural reaction to acellular dermis can lead to induration, palpable scarring, and the potential for further diagnostic studies and/or invasive procedures, to properly rule out recurrent disease.
Donald W. Buck, II, M.D.
Kamaldeep Heyer, B.S.
Jeffrey D. Wayne, M.D.
Anjana Yeldandi, M.D.
John Y. S. Kim, M.D.
The authors have no research relationship or conflict of interest to report with regard to this research.
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5. Bellows CF, Albo D, Berger DH, Awad SS. Abdominal wall repair using human acellular dermis. Am J Surg.
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