Plastic and Reconstructive Surgery

Skip Navigation LinksHome > February 2014 - Volume 133 - Issue 2 > Changing Role of Hyaluronidase in Plastic Surgery
Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e3182a4c282
Cosmetic: Special Topics

Changing Role of Hyaluronidase in Plastic Surgery

Bailey, Steven H. M.D.; Fagien, Steven M.D.; Rohrich, Rod J. M.D.

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Summary: Soft-tissue augmentation has become an increasingly popular option for facial rejuvenation. Hyaluronic acid fillers are part of the most rapidly expanding segment of this market, largely because of their safe drug profile and temporary nature. Despite their good safety profile, they can and do have complications ranging from superficial placement, uneven placement, granulomatous reactions, and skin necrosis. This article reviews the on- and off-label uses of hyaluronidase and presents several clinical algorithms detailing the effective and safe use of hyaluronidase to manage complications secondary to hyaluronic acid fillers.

©2014American Society of Plastic Surgeons


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